WASHINGTON (AP) — The Trump administration on Thursday intensified its sweeping efforts to shrink the size of the federal workforce, the nation’s largest employer, by ordering agencies to lay off nearly all probationary employees who had not yet gained civil service protection — potentially affecting hundreds of thousands of workers.

The Trump administration broadened its effort to terminate thousands of probationary workers on Thursday, instructing agencies on a call to move forward with the layoffs.

Almost half of the probationary workers at the U.S. Centers for Disease Control and Prevention and others at the National Institutes of Health are being forced out as President Donald Trump overhauls government agencies,