Zebrafish protein unlocks dormant genes for heart repair Date: January 2, 2025 Source: Hubrecht Institute Summary: Researchers have successfully repaired damaged mouse hearts using a protein from ...

Heart attacks are dangerous not just because of the initial event, but the long-term damage afterwards. Now scientists have ...

Using the zebrafish, a model species for heart studies, scientists decoded the IcNS’s molecular, cellular, and functional diversity. “This ‘little brain’ has a key role in maintaining and ...

Researchers from the Hubrecht Institute and their collaborators at other institutions have used a protein from zebrafish dubbed Hmga1 which plays a key role in heart regeneration, to reactivate ...

Artistic representation of heart regeneration: Hmga1 in green symbolically flows from the border zone of a zebrafish heart (top right) to the injured border zone of a mouse heart (left).

They discovered that the protein Hmga1 plays a key role in heart regeneration in zebrafish. In mice, this protein was able to restore the heart by activating dormant repair genes without causing ...

Researchers from the Bakkers group at the Hubrecht Institute have successfully repaired damaged mouse hearts using a protein from zebrafish. They discovered that the protein Hmga1 plays a key role in ...