Figure 1: Regulatory checkpoints of peripheral ... levels may disrupt cellular homeostasis. Elucidation of COX-2 regulatory pathways will lead to the development of new anti-inflammatory agents.

They block the effects of special enzymes -- specifically Cox-1 and Cox-2 enzymes. These enzymes play a key role in making prostaglandins. By blocking the Cox enzymes, NSAIDs stop your body from ...

Meloxicam is an enolcarboxamide with preferential COX-2 inhibitory activity. In vitro studies with human tissues have confirmed the high affinity of meloxicam for COX-2, whereas COX-1 was ...

Although the effects of anti-inflammatory drugs have been well studied, little is known about the signaling pathways involved ... expressed COX-1 and an inducible COX-2 isoform 6.

EA at acupoint ST36 improves burn-induced delays in gastric emptying by down-regulating COX-2 and pro-inflammatory cytokines through the autonomic nervous pathway. Full text https://www ...

Aspirin and COX-1 inhibitors boost immunity against cancer metastasis, revealing a new pathway for anti-metastatic therapies.