Nuclear DNA does not appear in free linear strands; it is highly condensed and wrapped around histones in order to fit inside of the nucleus and take part in the formation of chromosomes.

wrapped around an octamer of histones. An understanding of the folding mechanism that leads to a high compaction of the chromatin filaments in chromosomes has been a major scientific challenge for ...

Each eukaryotic chromosome is composed of DNA coiled and condensed around nuclear proteins called histones. Humans inherit one set of chromosomes from their mother and a second set from their father.

Inactivation of one X chromosome occurs in XX female cells to bring about ... immunoprecipitated acetylated isoforms of the four core histones in mouse embryonic stem (ES) cells and assayed DNA ...

Nucleosomes are re-assembled on the daughter chromosomes behind the replication fork from both parental nucleosomes and de novo from newly synthesized histones. Intriguingly, several replisome ...