Just five days after a historic loss at Old Trafford, Manchester United must travel to Anfield and take on a Liverpool side unbeaten in its last 23 matches.

Ruben Amorim will welcome two first-team regulars back from suspension against Liverpool this afternoon and there could be even more changes after Monday's shocking performance versus Manchester City

Man United will be eyeing their first Premier League win in more than a month when they welcome Southampton to Old Trafford on Thursday night.

Liverpool will play their first match of the new year when they host Manchester United in the Premier League on Sunday. Details of the lineups will appear here

Fernandes is a guaranteed starter after suspension, likewise Hojlund amid a lack of alternatives to lead the line. Mainoo was a bright spark off the bench against Newcastle and could be a starter as one of the No.10s, dropping deep to help Casemiro and Ugarte in the centre when United do not have the ball.

I have a lot of admiration for Manchester United's performance in their FA Cup win against Arsenal, especially to grind it out with 10 men for an hour after Diogo Dalot was sent off. I do not want to devalue what United did against Arsenal or Liverpool but they were games where the expectation was not on them to get results.

Southampton make the long trip to Manchester United in the Premier League this evening.The Saints are rooted to the bottom of the Premier League table and have won just six points since promotion.

Man Utd predicted XI against Southampton in the Premier League fixture on Thursday night.

This article will contain analysis and the best tips on the Manchester United vs Southampton fixture in the Premier League