Although differentiation and activity of bone-forming osteoblasts are regulated at various levels, there is ample evidence ...

A new review was published in Oncotarget's Volume 15 on August 2, 2024, entitled, “Targeting WNT5B and WNT10B in osteosarcoma ...

Financial writer rates Mereo BioPharma stock as Hold despite recent positive data, citing uncertainties around Phase 3 ...

Hormone balance plays a role in maintaining bone density and strength. Progesterone aids in bone formation by supporting osteoblast (bone-building) activity, while estriol helps regulate the uptake of ...

Vibration therapy is a rehabilitation method that uses mechanical oscillations or vibrations to stimulate the body. Research suggests it may improve posture, increase range of motion, promote ...

Growth, bone density, histology and fracture number are important outcome parameters, but are not simple to measure accurately and reproducibly in children with severe OI. For example, using ...

Prevention & Treatment Issues, Data & Hypotheses The first step would be to prevent PPI overuse by evaluating the appropriateness of PPI therapy. No data exist to prevent PPI and H 2 RA effects on ...

Metabolic rewiring is essential for osteoclast differentiation and bone resorption. This study shows that glutaminolysis ...

A large segment of the CYP2C19 rapid metabolizer subgroup is nonresponder to the PPI treatment, only partial symptom relief in GERD, more frequent unsuccessful eradication therapy and lower ...

LOWERING of the serum alkaline phosphatase activity has received little attention. 1 It is known in scurvy and hypophosphatasemia and after exposure to radioactive substances that are deposited in ...

In a significant development for osteoporosis treatment in the UK, the National Institute for Health and Care Excellence (NICE) has approved abaloparatide, a highly effective anabolic therapy, for ...