T he hypothalamus–pituitary–target gland axis has been recognized as a fundamental functional framework of the mammalian ...

The hypothalamic–pituitary–thyroid axis plays a crucial role in the pathogenesis, diagnosis, risk stratification, effectiveness of radioiodine therapy, and treatment response evaluation in epithelial ...

A mathematical model suggests that existing HPA-targeting drugs failed in clinical trials for mood disorders because the ...

The Pituitary Center offers: The pituitary gland lies at the base of the skull, between the brain and the paranasal sinuses. From this location, it serves a critical link between the brain and the ...

Pituitary diseases are disorders affecting the pituitary gland that ultimately affect the secretion of pituitary hormones. The most frequent conditions are acromegaly (growth hormone excess ...

Sleep disruption as a consequence of shift work can result in disruption of the hypothalamic-pituitary gland axis, which in turn triggers an increased release of glucocorticoids. A resulting ...

The action of the peptide hormone adrenocorticotropin (ACTH) to stimulate glucocorticoid production by the adrenal gland is an ... the hypothalamo–pituitary–adrenal axis is overactive, or ...