Much of the difficulty of determining the contributions of individual residues to protein structure and function stems from the need to generate and evaluate a large number of mutants. The ...

Proteins are the building blocks of life. They consist of folded peptide chains, which in turn are made up of a series of ...

"For the first time, we have managed to capture the full structure of native RBP3 in pigs with a resolution of 3.67 Å. This ...

Why do problems occur with a special variant of ‘protein glues’, the split inteins, that severely limit their use in ...

Their work suggested that this new function of RAD52 facilitates the survival of cancer cells. In the new study, Spies’ team ...

Northwestern University researchers have identified structural features in engineered cell receptors that correlate with ...

Although the rational protein design approach offers an increased possibility of beneficial alterations, it is not easy to accurately predict the sequence-structure-function relationship, particularly ...

Our skin and mucous membranes are protected by epithelial cells, which form a barrier that defends the body from the outside ...

Vitamin C is required for the manufacture of collagen, a protein that provides structure to the cornea and sclera (white of ...

A study from Cornell researchers could enable a quantum leap forward in identifying and deciphering cancer-driving genetic ...

Purdue University scientists have discovered a key mechanism that regulates how plants develop chloroplasts, essential ...

The information DNA contains is the instructions that the cell uses to make proteins. Proteins play a big part in determining the characteristics of specialised cells and whole organisms.