The best argument for grabbing a 5080 right now, if you can find one at $999 in the first place, is that the only cards that come close to its performance are either way more expensive than they're supposed to be (the 4080 Super) or not cheap enough to justify the Nvidia-specific features you give up (AMD's Radeon 7900 XTX).

Nvidia followed up the most powerful GPU it’s ever made, the RTX 5090, with this — the RTX 5080. It’s half the price, and it offers around 70% of the performance. That should be a good thing, but the RTX 5080 falls short when compared to Nvidia’s last-gen offerings that still rank among the best graphics cards.