As mentioned previously, medically managed treatment of severe aortic stenosis has a dismal prognosis, with an overall mean survival of 3 years from the onset of symptoms. [11,12] Surgical valve ...

When aortic stenosis occurs, there is a tightening and oftentimes calcification of the aortic ... And then finally severe, where the valve is so rigid that it's not opening enough to feed the ...

Patients with low-gradient aortic stenosis and reduced LVEF, compared with patients with high-gradient aortic stenosis, have worse clinical outcomes.

Aortic stenosis (AS) occurs when the orifice of the aortic valve is significantly reduced due to the failure of the aortic valve leaflets to open fully during systole. This causes an effective ...

A ratio of <0.25 is generally consistent with severe ... of calcification and doming of the aortic cusps in systole. Left ventricular outflow tract (LVOT) diameter may be measured for valve ...

Transcatheter aortic valve replacement or implantation (TAVR or TAVI) is a well-established treatment option for elderly patients with severe aortic ... annulus or leaflet calcification for ...

Large and rare duplications and deletions in a chromosome region known as 22q11.2 , which involves genes that regulate ...

The only effective treatment for aortic stenosis is removal of the mechanical obstruction. To this end, only aortic valve replacement (AVR) has been shown to achieve this while reducing mortality.