Subtle signs of neurodegeneration can be detected in blood, CSF, and neuroimaging, up to 20 years before the motor symptoms ...

CAMBRIDGE, Massachusetts ‒ For decades it's been one of the defining mysteries of Huntington's disease. Why does the terrible devastation of mind and body start earlier in some people who ...

COPD is a progressive lung disease with mild symptoms in the early stages that gradually worsen. Early diagnosis and treatment can help preserve lung function. People with COPD often have trouble ...

A new study of nerve cells affected by Huntington’s disease (HD ... the brains of patients who died while in different stages of the disease. To their surprise, they found that the length ...

Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating hereditary disorder that strikes in the prime of life.

Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating and fatal hereditary disorder that strikes in the prime of life, causing nerve cells in parts of the ...

Huntington’s disease is horrible. It is also odd. Illnesses caused by inherited aberrant genes are mostly what geneticists call “recessive”, meaning someone must receive defective versions ...

A recent study published in Cell reveals that the repeated DNA sequence that leads to Huntington’s disease (HD) expands ...

This type of "somatic expansion" occurs in only the specific types of brain cells that later die in Huntington's disease. Only once a cell's DNA expansion reaches a threshold number of CAGs ...

The field of Huntington’s disease research has been undergoing a radical reshaping of how the brain-ravaging disease — and what drives it — is understood. After decades focused on the notion ...