The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK ...
Program in Chemical Biology, Department of Chemical Physiology and Biochemistry, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, Oregon 97239, United States ...
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Single nucleus RNA sequencing (snRNA-seq), an alternative to single cell RNA sequencing (scRNA-seq), encounters technical challenges in obtaining high-quality nuclei and RNA, persistently hindering ...
The basis behind this theory is that segments of DNA that occur at the end of chromosomes, called telomeres ... Our genes are contained in our DNA which is present in the nucleus (inner area) of each ...
And our chromosomes, although safely ensconced within the cell’s nucleus, are far from stable. A piece of genetic code from another chromosome, or even from a virus, can embed itself into the ...
In this study, we aimed to evaluate the effect of bone-marrow-MSCs (BM-MSCs) and adipose-derived stromal cells (ADSCs) secretomes on human nucleus pulposus cells (hNPCs) in vitro. Methods: BM-MSCs and ...
Libraries were pooled and sequenced on an Illumina NovaSeq S1 flow cell with a goal to generate 50,000 reads per nucleus with a sequencing configuration of 28 base pair (bp) on read1 and 91 bp on read ...