particularly calcific aortic valve disease (CAVD), is a significant health concern characterized by the thickening and calcification of the aortic valve leaflets. This condition can lead to ...

When aortic stenosis occurs, there is a tightening and oftentimes calcification of the aortic ... And then finally severe, where the valve is so rigid that it's not opening enough to feed the ...

There are three main forms of aortic valve disease: congenital abnormalities, such as a bicuspid valve that leads to premature calcification; calcification of the normal trileaflet valve ...

Patients with low-gradient aortic stenosis and reduced LVEF, compared with patients with high-gradient aortic stenosis, have worse clinical outcomes.

Aortic stenosis (AS) occurs when the orifice of the aortic valve is significantly reduced due to the failure of the aortic valve leaflets to open fully during systole. This causes an effective ...

A ratio of <0.25 is generally consistent with severe ... of calcification and doming of the aortic cusps in systole. Left ventricular outflow tract (LVOT) diameter may be measured for valve ...

Large and rare duplications and deletions in a chromosome region known as 22q11.2 , which involves genes that regulate cardiac development, are linked to nonsyndromic bicuspid aortic valve disease, ...

Transcatheter aortic valve replacement or implantation (TAVR or TAVI) is a well-established treatment option for elderly patients with severe aortic ... annulus or leaflet calcification for ...

The only effective treatment for aortic stenosis is removal of the mechanical obstruction. To this end, only aortic valve replacement (AVR) has been shown to achieve this while reducing mortality.