Cancer cells thrive in an environment deprived of oxygen and nutrients, adapting to survive and grow. Unlike normal cells, ...
More information: Haowen Jiang et al, The Warburg effect drives dedifferentiation through epigenetic reprogramming, Cancer ...
This phenomenon is called the Warburg effect. Researchers spent the next several decades trying to figure out why cancer cells survive without oxygen. Some developed a hypothesis that low oxygen ...
Our study suggests that FLT3/ITD mutation promotes Warburg effect, and such metabolic alteration can be exploited to develop effective therapeutic strategy for treatment of AML with FLT3/ITD ...
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