BMJ2d
Mechanical overloading promotes chondrocyte senescence and osteoarthritis development through downregulating FBXW7
Objectives To investigate the role of mechanical stress in cartilage ageing and identify the mechanistic association during osteoarthritis (OA) progression. Conclusions FBXW7 is a key factor in the ...
BMJ2d
Global, regional and national burden of osteoarthritis 1990-2017: a systematic analysis of the Global Burden of Disease Study 2017
Objectives To report the level and trends of prevalence, incidence and years lived with disability (YLDs) for osteoarthritis (OA) in 195 countries and territories from 1990 to 2017 by age, sex and ...
BMJ3d
Adalimumab dose tapering in patients with rheumatoid arthritis who are in long-standing clinical remission: results of the phase IV PREDICTRA study
Objective To investigate the association between baseline disease activity and the occurrence of flares after adalimumab tapering or withdrawal in patients with rheumatoid arthritis (RA) in sustained ...
BMJ3d
Ultrasensitive serum interferon-α quantification during SLE remission identifies patients at risk for relapse
1 Sorbonne Université, Assistance Publique–Hôpitaux de Paris, Groupement Hospitalier Pitié–Salpêtrière, French National Referral Center for Systemic Lupus Erythematosus, Antiphospholipid Antibody ...
BMJ4d
Molecular signature characterisation of different inflammatory phenotypes of systemic juvenile idiopathic arthritis
Objectives The International League of Associations for Rheumatology classification criteria define systemic juvenile idiopathic arthritis (SJIA) by the presence of fever, rash and chronic arthritis.
BMJ13d
Myeloid-related proteins S100A8/S100A9 regulate joint inflammation and cartilage destruction during antigen-induced arthritis
Dr P van Lent, Department of Rheumatology, UMC Nijmegen, Building 850, Geert Grooteplein 26–28, Nijmegen, The Netherlands; P.vanlent{at}reuma.umcn.nl Objective: To study the active involvement of ...
BMJ2d
Characterising arthralgia in the preclinical phase of rheumatoid arthritis using MRI
Correspondence to HW van Steenbergen, Department of Rheumatology, Leiden University Medical Center, P O Box 9600, Leiden 2300 RC, The Netherlands; h.w.van_steenbergen{at}lumc.nl Background The phase ...
BMJ4d
2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative
41 St. Joseph's Health Care London and University of Western Ontario, London, Ontario, Canada Objective The 1980 American College of Rheumatology (ACR) classification criteria for systemic sclerosis ...
BMJ5d
Tofacitinib for the treatment of ankylosing spondylitis: a phase III, randomised, double-blind, placebo-controlled study
Objective To assess the efficacy/safety of tofacitinib in adult patients with active ankylosing spondylitis (AS). Methods This phase III, randomised, double-blind, placebo-controlled study enrolled ...
BMJ8d
Withdrawal of low-dose prednisone in SLE patients with a clinically quiescent disease for more than 1 year: a randomised clinical trial
1 Sorbonne Université, Assistance Publique–Hôpitaux de Paris, Groupement Hospitalier Pitié–Salpêtrière, French National Referral Center for Systemic Lupus Erythematosus, Antiphospholipid Antibody ...
BMJ2d
AB0146 HAND AND WRIST ACTIVE RANGE OF MOTIONS AND CONTRIBUTING FACTORS IN RHEUMATOID ARTHRITIS: A CROSS-SECTIONAL STUDY
Background: Patients with rheumatoid arthritis (RA) usually impaired range of motions (ROMs), especially hand and wrist active ROMs (AROMs), thus influencing their ability to perform daily activities ...
BMJ2d
POS1604 IL-13 INHIBITION USED FOR ATOPIC DISEASES IS ASSOCIATED WITH RISK OF PSORIATIC ARTHRITIS
1 University of Manchester, Centre for Epidemiology Versus Arthritis, Manchester, United Kingdom 2 Manchester University NHS Foundation Trust, NIHR Manchester Biomedical Research Centre, Manchester, ...