GLENDALE -- San Francisco 49ers RB Isaac Guerendo was carted off the field in Week 18's matchup against the Arizona Cardinals. He has already been ruled out with a knee and ankle injury. On just the ...

The Arizona Cardinals and San Francisco 49ers are locked into a Week 18 battle in their finale at State Farm Stadium later today. For one last time, you'll be able to place some cold hard cash on the ...

San Francisco 49ers quarterback Brock Purdy is dealing with a nerve issue in his elbow, and he is not expected to play in Week 18 against the Arizona Cardinals.

ESPN Analyst Ryan Clark says he believes Baltimore Ravens quarterback Lamar Jackson is the best player in the NFL and thinks ...

The 49ers are about to be in an extremely intriguing situation in 2025. No, I’m not talking about a big Brock Purdy extension or free agency, ...