Buffalo is an 8.5-point favorite in the latest Broncos vs. Bills odds, while the over/under for total points scored is 47. Before you make any Broncos vs. Bills picks, make sure to check out the NFL predictions and betting advice from the SportsLine expert Matt Severance,

Denver is 10-7 and secured its playoff spot with a 38-0 victory over the Chiefs backups. The Broncos are 5-2 in the last seven games and scored at least 24 points in all seven. However, this will be rookie QB Bo Nix’s first playoff start and Sean Payton’s first postseason game with Denver.

Shortly after Denver ended its eight-season playoff drought with a 38-0 blowout win over the Chiefs on Sunday, the wives and partners of Broncos players took to social media to celebrate as the team prepares to face the Bills on the road in the wild-card round.

The Denver Broncos (10-7) are considered big underdogs against the Buffalo Bills (13-4) going into the Wild Card round of the NFL playoffs. The Broncos are listed a 8.5-point underdogs going into the Bills game,

Thanks to their blowout win over the Kansas City Chiefs, the Denver Broncos are in the playoffs as the No. 7 seed in the AFC. Game update (Saturday night): With the Bengals’ win, the Broncos need to win if they want to be in the playoffs.