New research has investigated the mechanism by which bivalency functions to poise genes for expression during cell differentiation, providing insight into a long-standing paradigm in the regulation of ...

As well as being essential in the precise packaging of DNA into the space of the nucleus, histone proteins are also the site ...

Scientists published a full genetic sequence of the genes that make some white campions male, and hope their work could ...

Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.

There is evidence that Crohn’s disease is genetic, though environmental factors may also be involved. Crohn’s disease is a type of inflammatory bowel disease (IBD) that causes inflammation in ...

Chromosomes are tightly coiled structures in each of your cells that contain DNA, the code for all life. DNA is organized in segments on chromosomes called genes. Humans typically have 46 ...

The lab further learned that the enzyme responsible for modifying histones with serotonin and dopamine is transglutaminase 2 (TG2). In their latest study, researchers from the Nash Family ...

The last few years have provided us with a new level of understanding of how chromosomes are replicated, segregated and read - and how their 3D organisation influences expression of individual genes ...

Old histones are recycled during DNA replication ... However, the development of technologies such as chromosome conformation capture (3C) has led to a better characterization of long-range ...