Week 3 matchup vs. Rams with key injuries to McCaffrey, Samuel, and Kittle, testing their depth in this crucial NFC West ...

Herbert injured his right leg in the third quarter of Week 2’s 26-3 win against the Carolina Panthers trying to escape the ...

The San Francisco 49ers placed running back Christian McCaffrey on injured reserve on Aug. 14 but have yet to fill his vacant ...

With stud wide receiver (and quasi-backup running back) Deebo Samuel Sr. out in Week 3, San Francisco will continue to lean on Mason in a divisional matchup against the Rams. It's a smash opportunity ...

Injuries already are accruing across the NFL, knocking several star players out and forcing teams to turn to backups and ...

Nick Bosa had spoken to the media after the 49ers' 23-17 Week 2 loss to the Minnesota Vikings, where he explained how Fred ...

George Kittle and Charvarius Ward both missed practice Thursday, three days shy of the 49ers’ visit to Los Angeles where they ...

George Kittle was not in attendance for Thursday's practice session. According to ESPN's Adam Schefter, Kittle is experiencing tightness in ...

Defensive coordinator Nick Sorensen and run game coordinator and offensive line coach Chris Foerster reviewed the 49ers ...

With McCaffrey and Samuel out, Rams brace for 49ers' cunning tactics. Kobie Turner stresses the need for execution.