Sep 1, 2023 · The HPAI H5N1 virus is classified as a subtype of the influenza A virus, which belongs to the family Orthomyxoviridae. HPAI H5N1 virus genome consists of a negative single-stranded RNA molecule, spanning approximately 13.5 kilobases in length.

Jul 1, 2011 · Influenza virus A, subtype H5N1 infects birds and has been thought to have limited zoonotic potential and public health significance. In 1997, with the emergence and spread of the new Asian lineage H5N1 virus, this assumption has changed dramatically, as this virus is able to infect a broad spectrum of non-avian species, including humans ...

Feb 15, 2019 · Subtype H5N1, causing highly pathogenic avian influenza, was identified in humans in 1997 in Hong Kong. 1 Studies on the evolutionary dynamics of influenza A H5N1 indicate that the prototype virus (A/goose/Guangdong/1/96) was derived from a low pathogenic H5 subtype carried by migratory waterfowl, and introduced into poultry in 1996.

Oct 1, 2024 · In nondairy matrices, acidic and caustic conditions do promote H5N1 and other influenza virus decay at varying rates (Shahid et al., 2009; Wanaratana et al., 2010). Research is needed to determine what specific pH, hold times, and temperatures are required to reduce H5N1 loads to below detectable levels of infectious virus before disposal of ...

Jun 1, 2024 · Phylogenetic tree of H5N1 subtype influenza virus hemagglutinin (A) and neuraminidase (B) genes collected during the 2022–2023 outbreak in Peru. Data were downloaded from GISAID up to September 4, 2023. The final figure was obtained with Figtree. Samples sequenced by the INS in Peru are highlighted in bold and colored red.

Jan 6, 2010 · In early 2004, the outbreaks of avian influenza virus subtype H5N1 were reported in several Asian countries including South Korea, Vietnam, Japan, Taiwan, Laos, Cambodia, China, Pakistan, Indonesia and Thailand (OIE, 2004). In Thailand, the AIV subtype H5N1 epidemics caused severe losses to the poultry industry (OIE, 2004).

Mar 1, 2024 · The sensor was capable of differentiating the target H5N1 virus from other IAV subtypes with high specificity and sensitivity (LOD = 11.6 fM), and the detection of the virus could be enabled by fluorescence spectroscopy, UV–vis spectrophotometry, and colorimetric indication three modes, to provide a reliable point-of-care detection method for ...

Mar 23, 2022 · Influenza A viruses are classified based on differences in their two most abundant surface proteins, hemagglutinin (H) and neuraminidase (N), of which there are 16 and 9 different subtypes, respectively, that infect avian species; these occur in different combinations, defining the virus (e.g., H5N1). Human Influenza Virus comprises of Inf A ...

Feb 24, 2012 · The samples were processed for Influenza A (targeting Matrix gene) and H5 subtype (targeting HA gene) detection in one-step reverse transcription polymerase chain reaction (RT PCR) and real time RT PCR (Nagarajan et al., 2009, Nagarajan et al., 2010) followed by N1 virus subtype detection by one-step RT PCR (WHO, 2005).

Jan 3, 2024 · H5N1 AIV PB2 is a negative regulator of duMAVS-mediated type I IFN pathway A previous study demonstrated that the PB2 protein of H1N1 subtype influenza virus inhibited the production of type I interferon in A549 cells (Graef et al. 2010).